How does modafinil promote normal wakefulness?

Modafinil affects brain neurotransmitter systems to enhance wakefulness. Although its mechanism is unknown, it predominantly impacts dopamine, norepinephrine, and histamine levels. Modalert 200 mg Modafinil increases dopamine and norepinephrine, which regulate arousal and alertness, to improve wakefulness. Modafinil keeps people awake by increasing these neurotransmitters in wakefulness-related brain areas. Modafinil may also impact brain histamine levels, which may boost wakefulness. Modafinil modulates these neurotransmitter systems to promote normal alertness and minimize daytime drowsiness in narcolepsy, OSA, and shift work sleep disorder.